Which procedure examines muscle tissue structure?

• A. Muscle biopsy
• B. MRI
• C. CT scan
• D. Blood test

Answer: (A)

Direct examination of muscle tissue structure requires looking at the tissue itself under a microscope. A muscle biopsy collects a small piece of muscle that is then analyzed histologically to reveal fiber size variation,degeneration, inflammation, or replacement by fat and connective tissue—all of which inform muscular dystrophy diagnosis and subtype. Imaging tests like MRI or CT show overall muscle size, architecture, edema, or fat infiltration but do not reveal microscopic cellular structure. Blood tests detect enzymes or markers of muscle damage but not tissue architecture. So the procedure that directly examines muscle tissue structure is a muscle biopsy.