Which of the following is a common symptom cluster of MD?

• A. Seizures and memory loss
• B. Skin rash
• C. Weakness, fatigue, muscle wasting, cramping
• D. Hearing loss

Answer: (C)

Muscular dystrophy is defined by progressive weakness and loss of muscle mass due to genetic defects in muscle proteins. A typical symptom pattern is weakness with reduced endurance, leading to fatigue during activity, along with visible muscle wasting and sometimes cramps. This combination reflects the core issue: muscles become weaker over time, fatigability increases with use, and abnormal contractions can cause cramping after activity. Other options don’t fit MD as well: seizures and memory loss are neurologic features not central to MD; a skin rash points to dermatologic conditions; and hearing loss is not a defining feature of MD. So the hallmark cluster—weakness, fatigue, muscle wasting, and cramping—best describes the common symptom pattern of muscular dystrophy.