Which marker is elevated in muscular dystrophy due to muscle damage?

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Multiple Choice

Which marker is elevated in muscular dystrophy due to muscle damage?

Explanation:
Creatine kinase is elevated because it is released from damaged skeletal muscle fibers in muscular dystrophy. CK is highly concentrated in muscle, and when myofibers are damaged, the CK leaks into the bloodstream, causing marked increases—often far above normal. This makes CK a sensitive and relatively specific marker of skeletal muscle injury in MD. Other enzymes like AST and ALT come from multiple tissues (liver, heart, muscle) and LDH is even more nonspecific, so their elevations are not as diagnostic for muscle-specific damage.

Creatine kinase is elevated because it is released from damaged skeletal muscle fibers in muscular dystrophy. CK is highly concentrated in muscle, and when myofibers are damaged, the CK leaks into the bloodstream, causing marked increases—often far above normal. This makes CK a sensitive and relatively specific marker of skeletal muscle injury in MD. Other enzymes like AST and ALT come from multiple tissues (liver, heart, muscle) and LDH is even more nonspecific, so their elevations are not as diagnostic for muscle-specific damage.

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