What is a common respiratory complication in advanced DMD requiring ongoing management?

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Multiple Choice

What is a common respiratory complication in advanced DMD requiring ongoing management?

Explanation:
In advanced DMD, breathing muscles become weak, so the ability to ventilate properly declines, especially during sleep when muscles relax. This leads to hypoventilation and sleep-disordered breathing, a common issue that often requires ongoing management such as nocturnal noninvasive ventilation and regular airway clearance. Pneumonia can occur due to mucus clearance problems, and asthma or pulmonary fibrosis aren’t typical features of DMD progression, making hypoventilation with sleep-disordered breathing the hallmark challenge in this stage.

In advanced DMD, breathing muscles become weak, so the ability to ventilate properly declines, especially during sleep when muscles relax. This leads to hypoventilation and sleep-disordered breathing, a common issue that often requires ongoing management such as nocturnal noninvasive ventilation and regular airway clearance. Pneumonia can occur due to mucus clearance problems, and asthma or pulmonary fibrosis aren’t typical features of DMD progression, making hypoventilation with sleep-disordered breathing the hallmark challenge in this stage.

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