Weakness in DMD follows which pattern?

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Prepare for the Muscular Dystrophy Test with comprehensive flashcards and multiple-choice questions. Access detailed hints and explanations for each question to enhance your study experience. Equip yourself for success on your upcoming exam!

Multiple Choice

Weakness in DMD follows which pattern?

Explanation:
Duchenne muscular dystrophy weakens proximal muscles first, especially the hip and pelvic girdle, so individuals often have trouble rising from the floor (Gowers' sign). As the disease progresses, the weakness extends to the proximal muscles of the shoulders and upper arms, with distal muscles affected later. This proximal-to-distal pattern is characteristic, whereas distal-to-proximal patterns or facial-to-limb or trunk-to-limb sequences are seen in other conditions. Therefore, the weakness in DMD follows a proximal-to-distal progression.

Duchenne muscular dystrophy weakens proximal muscles first, especially the hip and pelvic girdle, so individuals often have trouble rising from the floor (Gowers' sign). As the disease progresses, the weakness extends to the proximal muscles of the shoulders and upper arms, with distal muscles affected later. This proximal-to-distal pattern is characteristic, whereas distal-to-proximal patterns or facial-to-limb or trunk-to-limb sequences are seen in other conditions. Therefore, the weakness in DMD follows a proximal-to-distal progression.

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