FSHD progression is described as which?

• A. Rapid progression with early disability
• B. No progression
• C. Fluctuating with remission
• D. Slow progression, often with normal life expectancy

Answer: (D)

FSHD typically follows a slow, steadily progressive course. Most people first notice weakness in facial muscles and shoulder girdle muscles, and the weakness gradually spreads over many years or even decades. Because the decline happens gradually, individuals often maintain functional independence for a long time, and life expectancy remains normal in many cases. This slow, progressive pattern contrasts with rapid deterioration, complete stability with no progression, or fluctuations with remissions. While severity can vary between people, the defining description is a slow progression with generally normal life expectancy.